All seminars will be held on Friday at 3:10 p.m. in 101 Roberts Hall unless otherwise noted.
David H. Kohn, M.S.E., Ph.D.
|University of Michigan
School of Dentistry and Department of Biomedical Engineering
|How Alterations in Mineral Affect Bone Mechanics and Bone Regeneration|
Our research program focuses on two aspects of biomineralization. First, we seek to understand how the organizational hierarchy of mineralized tissues results in mechanical competence (or, conversely, increased susceptibility to fracture), and how mineralized tissues adapt in response to environmental changes (e.g. alterations in mechanical loading, implantation of a biomaterial; disease; aging). The second component of our research program utilizes principles of biomineralization as a means of designing materials to repair and/or regenerate tissues. In this presentation, three specific research avenues are highlighted: 1) how mechanical loading of the skeletal system leads to compositional changes that increase mechanical competence and damage resistance, even in the absence of increasing bone mass; 2) how composition is altered in the bones of genetically modified animals and how mechanical loading can modulate genetic influences on skeletal competence; and 3) how alterations in diet can affect the structure and function of the skeletal system. Finally, examples of how biomaterials with surfaces that self-assemble bioactive mineral can be used as tissue regeneration templates and serve as platforms for modulating cell function will be presented.
Click here to download Adobe Acrobat Reader (in a new window). Adobe Acrobat Reader is required to open PDF files.
Thanks to the following speakers who have participated in the 2011-12 seminar series.
Judy Ramey, Ph.D., Professor in Department of Human Centered Design and Engineering
University of Washington
Richard E. Ladner, Ph.D., Boeing Professor in Computer Science and Engineering
University of Washington
Alex Cadotte, Ph.D.
Rob Abbott, Founder and President
Sree Sreenath, Prof., Dept. of Electrical Engineering & Computer Science and Dir. of the Complex Systems Biology Center
Case Western Reserve University
Mike Keller, President and CEO
Hybrid Power Technologies, LLC
Hassan Mahfuz, Ph.D., Professor
Department of Ocean and Mechanical Engineering
Florida Atlantic University
Brent Seales, Ph.D., Gill Professor of Computer Science and Director of the Center for Visualization and Virtual Environments
University of Kentucky
For further information on the seminars, or to visit with the speakers, please contact Anne Camper at firstname.lastname@example.org
Seminar series sponsored by the College of Engineering